Official publication of Rawalpindi Medical University
Frequency Of Raised Mean Platelet Volume In Patients With Acute Coronary Syndrome In HIT Hospital Taxila

Supplementary Files

PDF

How to Cite

1.
Batool F, Malik K, Meraj L, Tariq KM, Iqbal T, Zaka N. Frequency Of Raised Mean Platelet Volume In Patients With Acute Coronary Syndrome In HIT Hospital Taxila . JRMC [Internet]. 2023 Jun. 24 [cited 2024 Apr. 17];27(2). Available from: http://www.journalrmc.com/index.php/JRMC/article/view/2050

Abstract

To determine the frequency of raised Mean Platelet Volume (MPV) in patients with acute coronary syndrome (ACS) in HIT Hospital Taxila.

Materials and Methods: A case-control study was at HIT Hospital Taxila. All the patients presented with chest pain who fulfilled the inclusion criteria were recruited into the study. Patients with acute coronary syndrome were included in the case group (ACS group). The patients included in the control group (non-ACS group) had chest pain without having ischemic heart disease or risk of ischemic heart disease. Data were analyzed using SPSS version 28. To find out the correlation between the type of chest pain and mean platelet volume chi-square test was applied.

Results: Total 93 patients were included in this study. 51 patients were included in the ACS group while 42 were in non- ACS group. To find out the correlation between the type of chest pain and mean platelet volume chi-square test was applied. The results show a significant association between raised MPV and acute coronary syndrome.

Conclusion: Patients with raised MPV are at higher risk of acute coronary disease and complications related to it. It could be used as a predictor of ischemic heart disease and its complications.

https://doi.org/10.37939/jrmc.v27i2.2050

References

Shahab K, Mehr MT, Marwat MA, Amanullah. Quantification of mean platelet volume in diabetic patients presenting with cerebrovascular diseases. J Postgrad Med Inst 2016; 30(3): 268-71

Khode V, Sindhur J, Kanbur D, Ruikar K, Nallulwar S. Mean platelet volume and other platelet volume indices in patients with stable coronary artery disease and acute myocardial infarction: A case control study. J Cardiovasc Dis Res. 2012 Oct;3(4):272-5. doi: 10.4103/0975-3583.102694. PMID: 23233769; PMCID: PMC3516005.

Endler G, Klimesch A, Sunder‐Plassmann H, Schillinger M, Exner M, Mannhalter C, Jordanova N, Christ G, Thalhammer R, Huber K, Sunder‐Plassmann R. Mean platelet volume is an independent risk factor for myocardial infarction but not for coronary artery disease. British journal of haematology. 2002 May;117(2):399-404.

Korniluk A, Koper-Lenkiewicz OM, Kamińska J, Kemona H, Dymicka-Piekarska V. Mean platelet volume (MPV): new perspectives for an old marker in the course and prognosis of inflammatory conditions. Mediators Inflamm. 2019 Apr 17;2019:9213074. doi: 10.1155/2019/9213074.eCollection 2019.

Ranjith MP, Divya R, Mehta VK, Krishnan MG, KamalRaj R, Kavishwar A. Significance of platelet volume indices and platelet count in ischaemic heart disease. J ClinPathol. 2009 Sep; 62(9):830-3. doi: 10.1136/jcp.2009.066787.

Ihara A, Kawamoto T, Matsumoto K, Shouno S, Morimoto T, Noma Y. Relationship between hemostatic factors and the platelet index in patients with ischemic heart disease. Pathophysiology of haemostasis and thrombosis. 2006;35(5):388-91. doi:10.1159/000097694

Slavka G, Perkmann T, Haslacher H, Greisenegger S, Marsik C, Wagner OF, Endler G. Mean platelet volume may represent a predictive parameter for overall vascular mortality and ischemic heart disease. Arteriosclerosis, thrombosis, and vascular biology. 2011 May;31(5):1215-8. doi: 10.1161/ATVBAHA.110.221788.

Kishk YT, Trowbridge EA, Martin JF. Platelet volume subpopulations in acute myocardial infarction: an investigation of their homogeneity for smoking, infarct size and site. Clinical Science. 1985 Apr;68(4):419-25. doi: 10.1042/cs0680419. PMID: 3971672.

Madavi T, Bhole P, Holay MP. Mean platelet volume as a predictor of clinical outcomes in patients of acute myocardial infarction. Intl J Res Med Sci.2019 Feb; 7 (2): 388-393. DOI: https://doi.org/10.18203/2320-6012.ijrms20190340

Manchanda J, Potekar RM, Badiger S, Tiwari A. The study of platelet indices in acute coronary syndromes. Annals Pathol Labo Med. 2015 Jan 30;2(1):A30-5.

Khandekar MM, Khurana AS, Deshmukh SD, Kakrani AL, Katdare AD, Inamdar AK. Platelet volume indices in patients with coronary artery disease and acute myocardial infarction: an Indian scenario. J Clin Pathol. 2006;59(2):146-9.

Chu SG , Becker RC, Berger PB, Bhatt DL et al. Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-analysis. J Thromb Haemost.2010 Jan;8(1):148-56.

Yaghoubi A, Golmohamadi Z, Alizadehasl A, Azarfarin R. Role of platelet parameters and haematological indices in myocardial infarction and unstable angina. J Pak Med Assoc 2013; 63: 1133-1137

Tamer D, Fevzi Y, Deniz AE, Cemil K, Fatih B, Cihat Y, Serkan YM, Ali CM, Evvah KM. The value of serum mean platelet volume in ischaemic stroke patient. J Pak Med Assoc. 2013 Dec 1;63(63):1509-0.

Mahmood N, Anjum N, Khurram M,Salam A, Nazar M, Rafique S. Mean Platelet volume and Acute Stroke Patient Characteristics. J Pak Soc Intern Med. 2021;2(1):24-28

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Copyright (c) 2023 Lubna Meraj