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Abstract
Background: To study etiology of upper gastro-intestinal [GI] haemorrhage with flexible upper GI endoscopy.
Methods: 2484 patients who were endoscoped at DHQ Teaching Hospital, Rawalpindi, from October to December 2003, for evaluation of upper GI haemorrhage were included. Record of these patients that included patient characteristics, endoscopic diagnosis etc was analyzed using statistical program, SPSS version 8.
Results: Of the 2484 patients, 68% were female and 32% male. Mean patient age was 38.8 ± 12.6 years. Erosive gastritis [15.6%], esophago/gastro/duodenitis [15.3%], duodenitis [14.7%], varices [12.9%], and peptic ulcer disease [8.3%] were commonest endoscopic diagnosis. 24% patients had normal upper GI endoscopy.
Conclusion: Erosive gastritis, esophago/gastro/duodenitis, duodenitis, varices, and peptic ulcer disease are common causes of upper GI haemorrhage in our patients.
References
Dallal HJ, Palmer KR. Upper GI haemorrhage. BMJ 2001; 323: 1115-17.[cite: 2]
Wilcox CM, Clark WS. Causes and outcome of upper and lower GI bleeding: The Grady Hospital. SMJ 1999; 92(1): 44-50.[cite: 2]
Dam JV, Brugge WR. Endoscopy of the upper GI tract. NEJM 1999; 341(23): 1738-48.[cite: 2]
Goodwin CS, Armstrong JA, Marshall BJ. Campylobacter pylori, gastritis, and peptic ulceration. J Clin Pathol 1986; 39: 353-65.[cite: 2]
Hernandez-Diaz S, Rodriguez LAG. Association between nonsteroidal anti-inflammatory drugs and upper gastrointestinal tract bleeding/perforation: an overview of epidemiologic studies published in the 1990s. Arch Intern Med. 2000; 160: 2093-99.[cite: 2]
Wilcox CM, Shalek KA, Cotsonis G. Striking prevalence of over-the-counter nonsteroidal anti-inflammatory drug use in patients with upper gastrointestinal haemorrhage. Arch Internal Medicine 1994; 154(1): 42-46.[cite: 2]
Gilbert DA. The national ASGE survey on upper gastrointestinal bleeding: III. Endoscopy in upper gastrointestinal bleeding. Gastrointest Endosc 1981; 27: 94-102.[cite: 2]
Khurram M, Khaar HTB, Hasan Z, Umar M, Javed S, Asghar T, et al. A 12 years audit of upper gastrointestinal endoscopic procedures. JCPSP 2003; 13(6): 321-24.[cite: 2]
Laine L, Peterson WL. Bleeding peptic ulcer. NEJM 1994; 331(11): 717-23.[cite: 2]
Sharara AI, Rockey DC. Gastroesophageal variceal haemorrhage. NEJM 2001; 345(9): 669-81.[cite: 2]
Czernichow P, Hochain P, Nousbaum JB, Raymond JM, Rudelli A, Dupas JL, et al. Epedemiology and course of acute GI haemorrhage in four French geographical areas. Eur J Gastroenterol Hepatol 2000; 12(2): 175-81.[cite: 2]
Thomopoulous K, Katsakoulis E, Vagianos C, Mimidis K, Margaritis V, Nikolopoulou V. Causes and clinical outcome of acute upper GI bleeding: a prospective analysis of 1534 cases. Int J Clin Pract 1998; 52(8): 547-50.[cite: 2]
Depolo A, Dobrila-Dintinjana R, Uravic M, Grbas H, Rubinic M. Upper GI bleeding review of our ten years results. Zentalbl Chir 2001; 126(10): 772-76.[cite: 2]
Lakhwani MN, Ismail AR, Barras CD, Tan WJ. Upper GI bleeding in Kuala Lumpur Hospital, Malaysia. Med J Malaysia 2000 53(4): 498-505.[cite: 2]
Haghighat M. Acute upper GI haemorrhage in children: the role of endoscopy in diagnosis and treatment. Irn J Med Sci 1996; 21(1&2): 19-20.[cite: 2]
Khalid K, Salamah S. Variceal bleeding revisited: a clinicoepidemiological study. JCPSP 2001; 11(12): 754-58.[cite: 2]
Guzmán VG, Soto GM, Flores CA, Rico SE, Roesch DF, Garcia RV, et al. Frequency and causes of haemorrhage in the upper digestive tract in patients in Veracruz, Mexico. Cir Ciruj 2002; 70(1): 3-7.[cite: 2]
Pruthi HS, Sharma SK, Singh B, Anand AC. Aetiology of upper gastrointestinal haemorrhage an endoscopic study. Medical Journal Armed Forces India 2000; 56(3): 188-91.[cite: 2]
Hussain T, Mirza S, Saber S. Etiology and outcome of acute upper GI haemorrhage cases admitted to Military Hospital, Rawalpindi. Pak Armed Forces Med J 2001; 51(2): 111-16.[cite: 2]
Khokhar N. Management of acute upper GI haemorrhage. Pak Armed Forces Med J 2001; 51(1): 14-17.[cite: 2]
Nasir NU, Nadeem MA, Imran M, Hussain I, Chaudhry NU. Esophageal varices vs peptic ulcer: a study of 100 patients presenting in Mayo hospital with upper GI bleeding. Pak J Gastroenterol 1998; 12(1-2): 10-15.[cite: 2]
Ch AW. Pattern of upper GI bleeding at Sheikh Zayed Hospital, Rahimyarkhan and management of acute variceal bleeding. Abstract book of the 18th Gastroenterology Congress; 2002 May 2-5; Karachi, Pakistan; 2002. P. 72.[cite: 2]
Ul Wadood A, Rehman AU, Masud U, Mirza JA, Sahibzada NJ. Helicobacter associated gastritis a clinicopathological study at Quetta. Biomedica 1997; 13 (2): 57-59.[cite: 2]
Bushra HT, Umar M, Khan NY, Latif Z. Helicobacter pylori and chronic gastritis. Pak J Gastroenterol 1995; 9(2): 25-27.[cite: 2]
Kumar P, Clark M (editors). Epedemiology of peptic ulcer disease. In: Clinical medicine. 4th ed. Edinburgh, WB Saunders 1998: 237-38.[cite: 2]
Shrestha S. Gastric ulcers. eMedicine Journal [online] 2002 [cited 2004 January 21]. Available from URL: [http://www.emedicine.com/med/topic849.htm](http://www.emedicine.com/med/topic849.htm)[cite: 2]
Peterson WL, Barnett CC, Smith HJ, Allen MH, Corbett DB. Routine early endoscopy in upper GI bleeding. A randomized controlled trial. NEJM 1981; 304(16): 925-29.[cite: 2]
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Copyright (c) 2003 Muhammad Khurram, Saima Javed, Hamama tul Bushra Khaar, M Fayyaz Goraya, Zubair Hasan