Official publication of Rawalpindi Medical University
Platelet Distribution Width: A Severity Marker Of Pre Eclampsia, Experience At Tertiary Care Hospital

Supplementary Files

PDF

Keywords

pre-eclampsia.

How to Cite

1.
Zahir M, Sial SS, Noreen H. Platelet Distribution Width: A Severity Marker Of Pre Eclampsia, Experience At Tertiary Care Hospital. JRMC [Internet]. 2023 Jun. 24 [cited 2024 Apr. 17];27(2). Available from: http://www.journalrmc.com/index.php/JRMC/article/view/2067

Abstract

Objectives: To determine mean platelet distribution width in patients with pre-eclampsia.

Study design: This is a cross-sectional, descriptive study performed in the Department of Obstetrics and Gynecology, Benazir Bhutto Hospital, Rawalpindi, retrospectively from 01 May 2017 to 01 November 2017 by non-probability consecutive sampling technique.

Materials & Methods: A total of 150 pregnant females with mild and severe pre-eclampsia with gestational age > 20 weeks, and an age limit of 18-40 years were included in the study. Patients having deranged coagulation or multiorgan involvement were excluded. Blood and urine samples were collected at the time of presentation. All the blood pressure readings were confirmed by two readings 4-6 hours apart. Mean ± SD was used to express data values. The mean PDW value was calculated for pregnant females with mild and severe preeclampsia.

Results: In our study Mean PDW in patients with preeclampsia was 15.86± 0.34. The mean PDW for mild preeclampsia was 15.8± 0.35 and for severe preeclampsia 15.98±0.28..

Conclusion: PDW is a useful marker for the prediction of the severity of preeclampsia before the disease progresses to severe preeclampsia and HELLP. Raised values can help the obstetrician to actively manage the patients in time to reduce maternal and fetal mortality.

https://doi.org/10.37939/jrmc.v27i2.2067

References

Yang SW, Cho SH, Kwon HS, Sohn IS, Hwang HS. Significance of the platelet distribution width as a severity marker for the development of preeclampsia. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2014 Apr 1;175:107-11.

Karateke A, Kurt RK, Baloğlu A. Relation of platelet distribution width (PDW) and platelet crit (PCT) to preeclampsia. Ginekologia polska. 2015;86(5).

Freitas LG, Alpoim PN, Komatsuzaki F, Carvalho MD, Dusse LM. Preeclampsia: are platelet count and indices useful for its prognostic?. Hematology. 2013 Nov 1;18(6):360-4.

Bawore SG, Adissu W, Niguse B, Larebo YM, Ermolo NA, Gedefaw L. A pattern of platelet indices as a potential marker for prediction of pre-eclampsia among pregnant women attending a Tertiary Hospital, Ethiopia: A case-control study. Plos one. 2021 Nov 9;16(11):e0259543.

Doğan K, Guraslan H, Senturk MB, Helvacioglu C, İdil S, Ekin M. Can platelet count and platelet indices predict the risk and the prognosis of preeclampsia?. Hypertension in pregnancy. 2015 Oct 2;34(4):434-42.

Dadhich S, Agrawal S, Soni M, Choudhary R, Jain R, Sharma S, Saini SL. Predictive value of platelet indices in development of preeclampsia. J SAFOG. 2012 Jan;4(1):17-21.

Hutcheon JA, Lisonkova S, Joseph KS. Epidemiology of pre-eclampsia and the other hypertensive disorders of pregnancy. Best practice & research Clinical obstetrics & gynaecology. 2011 Aug 1;25(4):391-403.

Young BC. Levine rJ, karumanchi sA Pathogenesis of preeclampsia. Annu. rev. Pathol. 2010;5:173-92.

Vijaya C, Lekha MB, Shetty A, Geethamani V. Evaluation of platelet counts and platelet indices and their significant role in pre-eclampsia and eclampsia. Journal of Evolution of Medical and Dental Sciences. 2014 Mar 24;3(12):3216-20.

AlSheeha MA, Alaboudi RS, Alghasham MA, Iqbal J, Adam I. Platelet count and platelet indices in women with preeclampsia. Vascular health and risk management. 2016 Nov 21:477-80.

Umezuluike BS, Anikwe CC, Nnachi OC, Iwe BC, Ifemelumma CC, Dimejesi IB. Correlation of platelet parameters with adverse maternal and neonatal outcomes in severe preeclampsia: A case-control study. Heliyon. 2021 Dec 1;7(12):e08484.1.

Thalor N, Singh K, Pujani M, Chauhan V, Agarwal C, Ahuja R. A correlation between platelet indices and preeclampsia. Hematology, transfusion and cell therapy. 2019 Jun 10;41:129-33.

Singh A, Varma R. Role of platelet distribution width (PDW) and plateletcrit in the assessment of nonthrombocytopenic preeclampsia and eclampsia. The Journal of Obstetrics and Gynecology of India. 2018 Aug;68:289-93.

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Copyright (c) 2023 Mariam Zahir