TY - JOUR AU - Shazia Syed ,Humera Noreen ,Humaira Masood ,Ismat Batool ,Hina Gul ,Nighat Naheed, PY - 2020/08/16 Y2 - 2024/03/28 TI - COVID-19 and Pregnancy Outcome: An Experience in ‘COVID-19 Management Designated’ Tertiary Care Hospital, Rawalpindi, Pakistan JF - Journal of Rawalpindi Medical College JA - JRMC VL - 24 IS - Supp-1 SE - Articles DO - 10.37939/jrmc.v24iSupp-1.1453 UR - https://www.journalrmc.com/index.php/JRMC/article/view/1453 SP - AB - <p><strong>B</strong><strong>ackground:</strong> The current COVID-19 pandemic has affected almost 17.3 million victims worldwide with mortality of almost 674K. Pregnancy is one of the most susceptible conditions for COVID-19 infection, but limited data is currently available about the clinical characteristics of pregnant women with the disease. <strong>Objective; </strong>to describe the clinical characteristics, co-morbidities, management, feto-maternal, and neonatal outcome in COVID-19 positive pregnant women.</p><p><strong>Methodology: </strong>A descriptive case series study was conducted in Obs/Gynae dept of Benazir Bhutto Tertiary Care Hospital, Rawalpindi, including all asymptomatic/symptomatic COVID-19 positive pregnant women and clinical suspects (COVID-19 PCR negative women) delivered in our hospital from 01<sup>st</sup> April 2020 to 31<sup>st</sup> July 2020. Their medical records were reviewed for clinical characteristics, management, feto-maternal and neonatal outcomes. Continuous variables were expressed in Mean &amp; Range and Categorical variables as number &amp; Percentage. <strong>Results:</strong> During the study period a total of 17 cases were reviewed. The mean maternal age was 28.94 yrs. Primigravida (07), Multipara (10). Mean gestational age was 37 wks (range; 30-41wks). Presenting symptomatology was varied. Asymptomatic; (29%), COVID-19 specific symptoms; fever &amp; flu (12%), fever&amp;cough (6%), shortness of breath(SOB) alone (6%), fever &amp; SOB(6%) and pregnancy-related manifestations were labour pains (17%), eclampsia(6%), hydrocephalous fetus (6%) and hepatic encephalopathy(6%). The commonest co-morbidity was Hypertensive disorders of pregnancy (24%). Five women (29%) required ICU care. Lower segment caesarean sections(LSCS) (59%), vaginal delivery (41%). Eleven babies delivered with good Apgar score and birth weight. Two were early neonatal deaths (ENND) and 04 were received intra-uterine fetal deaths (IUDs). Fetal demise was associated with strong obstetric risk factors. Out of 13 live-born babies, RT-PCR Covid-19 testing was done in 10 (77%) cases and was negative. One mother was expired due to complications of hepatic encephalopathy, sepsis, and burst abdomen.</p><p><strong>Conclusion;</strong> The clinical course of COVID-19 disease in pregnancy seems to be no different from non-pregnant women. Clinical manifestations are diverse and infection contracted in the third trimester of pregnancy is associated with good feto-maternal and neonatal outcomes.</p> ER -