Official publication of Rawalpindi Medical University
Factors Leading to Meconium Aspiration Syndrome in Neonates

How to Cite

Nusrat Buzdar, Rhodes Azeem, Muhammad Sajid Akhtar, Nadir Bashir NBRAMSANB. Factors Leading to Meconium Aspiration Syndrome in Neonates. JRMC [Internet]. 2017 Dec. 30 [cited 2023 Dec. 6];21(4). Available from:


Background: To determine the factors leading to meconium aspiration syndrome in neonates

Methods: In this descriptive study 100 neonates, with complaint of meconium staining of body, vocal cords and / or respiratory distress, whether delivered at home or at hospital, were included. Babies were first diagnosed as a case of meconium aspiration syndrome by meconium staining of body and vocal cords, and / or tachypnea and respiratory distress. They were examined for crepitations in chest on auscultation. Chest X-rays were done of all patients to see infiltrates and hyperinflation.

Results: The most frequent factor was birth asphyxia which was predicted by poor APGAR score (40% cases). The other factor was post term pregnancy(30%).  Males constituted 58%and 42% were females. One patient (1%) case was preterm and IUGR. While 30% cases were post-term and 69% cases were born by appropriate age.  60% cases were delivered by spontaneous vaginal delivery.  Commonest complications observed were  pneumothorax (15%) and sepsis. Chest X-Ray findings  showed infiltrates and hyper expansion in 50% cases.

Conclusion: Factors which lead to meconium aspiration syndrome are birth asphyxia, post term pregnancy, maternal diseases, prolong labour and IUGR