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Objective: To determine the association between vitamin D deficiency and urinary tract infections within the local population.
Methods: In this cross-sectional study, urine and blood samples of 174 participants (87 healthy controls and 87 UTI patients) were collected by standard operating procedures. Urine samples were processed for the physical, chemical, microscopic examination and culture & sensitivity. The disinfectant susceptibility examination was skilled by using the Kirby-Bauer disc diffusion test by CLSI recommendations. Vitamin D levels of the participants were determined in blood samples by the ELISA technique.
Results: Out of 87 urine samples of UTI patients, 84 (96.5%) were growth positive; out of these positive cases, Gram-negative bacteria were 75(89.3%) in comparison to Gram-positive bacteria, which were 8(9.5%), and 1(1.2%) was Candida albicans. In all of these isolates, Escherichia coli was the predominant 49(56.3%) uropathogens and a higher frequency was observed in young females. The majority of the UTI patients, 68(78.2%), revealed a vitamin D deficiency, compared to 5(5.7%) in the control group participants. There was a statistically significant difference (p-value .001).
Conclusion: This study highlights the strong correlation between vitamin D deficiency and UTI.
References
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