Official publication of Rawalpindi Medical University
Post-Menopausal Symptoms: Do They Affect A Woman’s Quality Of Life?

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Maqsood Z, Noreen H, Ejaz L, Bilqis H, Shaista, Arooj A. Post-Menopausal Symptoms: Do They Affect A Woman’s Quality Of Life?. JRMC [Internet]. 2025 Sep. 28 [cited 2025 Oct. 30];29(3). Available from: https://www.journalrmc.com/index.php/JRMC/article/view/2740

Abstract

Objective: Menopause is a physiological event and transition of life in all women at the age of 45. Assessment of Quality of life (QoL) at menopause has been largely inadequate. The study aims to assess the Quality of life in post-menopausal women of Pakistan

Methods: An Analytical cross-sectional study was conducted in the gynaecology/obs unit of Holy Family Hospital, after taking approval from the ethical review board. 580 women were included in the study. Data collection was facilitated through a questionnaire, administered by the gynaecology OPD duty doctor after conducting interviews with the postmenopausal women. The questionnaire was adopted from the Menopause Rating Scale (MRS) and the World Health Organisation Quality of Life (WHOQoL) proforma.

Results: Mean age at menopause was 49.9 years. Postmenopausal symptoms were experienced by 95% of women of varying severity, with the most commonly reported symptoms being hot flushes (79%), followed by palpitation (70%), depressive illness (45%), sexual problems/decreased libido 33% and urinary problems 25%. Around 16 per cent of women reported an effect on Quality of life due to menopausal symptoms. A positive correlation was found between QoL and the education of the patient. There was a negative correlation between QoL and parity and the age of the patient. In multiple regression analysis, vasomotor symptoms score (hot flashes and night sweats), psychological symptoms (depressive mood) and urogenital symptoms (sexual problem and bladder problem) remained as main predictive factors of QOL of postmenopausal women, accounting for 38% of variance (adjusted R2 =0.38).

Conclusion: The experience of menopausal symptoms varies across cultures and regions, impacting women's quality of life. Factors like symptom prevalence, parity, economic status, and cultural beliefs significantly shape the menopausal experience, highlighting the need for tailored support and interventions to improve women's well-being during this phase of life.

https://doi.org/10.37939/jrmc.v29i3.2740

References

Keye C, Varley J, Patton D. The impact of menopause education on quality of life among menopausal women: a systematic review with meta-analysis. Climacteric. 2023 Oct;26(5):419–27. https://doi.org/10.1080/13697137.2023.2226318.

Xu H, Liu J, Li P, Liang Y. Effects of mind body exercise on perimenopausal and postmenopausal women: a systematic review and meta analysis. Menopause. 2024 May;31(5):457–67. https://doi.org/10.1097/GME.0000000000002336.

Nilsson S, Henriksson M, Hammar M, Berin E, Sederholm Lawesson S, Ward LJ, et al. A 2 year follow up to a randomized controlled trial on resistance training in postmenopausal women: vasomotor symptoms, quality of life and cardiovascular risk markers. BMC Womens Health. 2024 Sep 13;24:511. https://doi.org/10.1186/s12905-024-03351-1.

Tang R, Fan Y, Ruan X, Zhang Z, Ren M, Wu J, et al. Changes in menopause specific quality of life between women with transdermal estradiol versus oral estrogens: results of a randomized controlled trial. Gynecol Endocrinol. 2025;41(1):2484213. https://doi.org/10.1080/09513590.2025.2484213.

Shorey S, Ang L, Lau Y. Efficacy of mind body therapies and exercise-based interventions on menopausal related outcomes among Asian perimenopause women: a systematic review and meta-analysis. J Adv Nurs. 2020 May;76(5):1098–110. https://doi.org/10.1111/jan.14310.

AlSwayied G, Guo H, Rookes T, Frost R, Hamilton FL. Assessing the acceptability and effectiveness of mobile based physical activity interventions for midlife women during menopause: systematic review of the literature. JMIR Mhealth Uhealth. 2022 Dec 9;10(12):e40271. https://doi.org/10.2196/40271.

Deva R, Manvi S, Zhou J, Chahine EB, Davenport Nicholson A, Kaonga NN, et al. A mixed methods evaluation of LLM based chatbots for menopause. arXiv. 2025 Feb 5;abs/2502.03579.

Fang Y, Liu F, Zhang X, Chen L, Liu Y, Yang L, et al. Mapping global prevalence of menopausal symptoms among middle aged women: a systematic review and meta analysis. BMC Public Health. 2024 Jul 2;24:1767. https://doi.org/10.1186/s12889-024-19280-5.

Liu H, Cai K, Wang J, Zhang H. The effects of mindfulness based interventions on anxiety, depression, stress, and mindfulness in menopausal women: a systematic review and meta-analysis. Front Public Health. 2022;10:104564. https://doi.org/10.3389/fpubh.2022.1045642. (supporting)

Review on psychosocial interventions in menopause: effects on non physiological symptoms. J Affect Disord. 2024; unspecified; https://doi.org/10.1016/j.jad.2024.**.

Women’s Study for the Alleviation of Vasomotor Symptoms: significant reductions in VMS and MENQOL scores with lifestyle intervention. Menopause. 2021 Oct;28(10):1245–52. https://doi.org/10.1097/GME.0000000000001834.

Yeganeh L, Vermeulen N, Ee C, Teede H, Vincent AJ. Lifestyle management in menopause: a systematic review of women with premature Ovarian insufficiency. Clinical Endocrinology. 2025 Feb 24. https://doi.org/10.1111/cen.15218.

Mohammady M, Janani L, Jahanfar S, Mousavi MS. Effect of omega 3 supplements on vasomotor symptoms in menopausal women: systematic review and meta analysis. Eur J Obstet Gynecol Reprod Biol. 2018;228:295–302.

https://doi.org/10.1016/j.ejogrb.2018.07.008

Boardman HM, Hartley L, Eisinga A, Main C, Roqué i Figuls M, Boyers D, et al. Hormone therapy for preventing cardiovascular disease in post menopausal women. Cochrane Database Syst Rev. 2015 Mar 10;(3):CD002229. https://doi.org/10.1002/14651858.CD002229.pub4

Syed Alwi SAR, Brohi IB, Awi IA. Perception of menopause among women of Sarawak, Malaysia. BMC Womens Health. 2021 Feb 22;21:77. https://doi.org/10.1186/s12905-021-01230-7.

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Copyright (c) 2025 Zainab Maqsood, Humera Noreen, Lubna Ejaz, Humaira Bilqis, Shaista, Amara Arooj