Official publication of Rawalpindi Medical University
Frequency of Modic Changes in Degenerative Disc Disease on Magnetic Resonance Imaging of Lumbar Spine
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Hina Nasir , Areej Umber Khan , Gul-e-Lala , Sadia Azmat. Frequency of Modic Changes in Degenerative Disc Disease on Magnetic Resonance Imaging of Lumbar Spine. JRMC [Internet]. 2016 Mar. 30 [cited 2024 Mar. 28];20(1). Available from: https://www.journalrmc.com/index.php/JRMC/article/view/208

Abstract

Background: To determine the frequency and distribution of endplate marrow signal intensity changes in patients with low back pain and to analyze their association with age and gender.
Methods: In this cross sectional study patients of ages 27-75 years, who came for MRI of lumbar spine with low back pain or sciatica, were included. The patients with age <25 years and >70 years with history of back surgery, trauma and malignancy were excluded. Imaging was performed on a 1.5 Tesla power magnetic resonance imaging machine. The imaging protocol included T1-weighted and T2 weighted, fast spin echo (FSE) sagittal and axial images. The intervertebral discs were graded as normal, Grade 1, Grade 2, Grade 3 and endplate bone marrow (Modic) changes were classified in three types according to the definitions of Modic et al. Findings were localized by disc segment (L1—L2, L2—L3, L3—L4, L4—L5, and L5— S1) and whether they were in the superior or inferior endplate. Frequencies and percentage was presented for categorical variables like gender, type of Modic change, vertebral level and intervertebral disc degeneration.
Results: Out of 177 patients 49.15% lumbar spine showed positive modic changes while in 50.85% changes were absent. Majority of the patients were between 31-40 years of age. Out of these 61.58% were male and 38.42% were female.
Conclusion: Modic changes are found frequently on MRI of spine in patients with degenerative changes and are associated with history of back ache. It gives useful information regarding the severity of degenerative disk disease.

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