@article{Muhammad Arham, Muhammad Arish, Jahangir Sarwar Khan_2018, title={Incidental Parasitic Infestations in Surgically Removed Appendices and its Association with Inflammation}, volume={22}, url={http://www.journalrmc.com/index.php/JRMC/article/view/846}, abstractNote={<p>Background:. To determine the frequency and<br>type of parasitic infestations in surgically removed<br>appendices based on histopathological findings and<br>to assess its association with inflammation.<br>Methods: In this cross-sectional study 471<br>appendices removed were included and their<br>histopathologic examination reports were observed.<br>In cases with parasitic infestations, information<br>regarding gender, age and presence of inflammation<br>was gathered. Fisher’s exact test at 5% level of<br>significance was applied to compare presence of<br>inflammatory infiltrates in appendices with and<br>without parasites.<br>Results: Of the 471 appendectomies performed, 15<br>(3.18%) specimens were found to contain parasites,<br>all of which were Enterobius vermicularis<br>(pinworm). In those 15 cases, age of patients ranged<br>from 9 to 45 years with a mean age of 19.07 ± 9.04<br>years. Out of those 15 patients, 11 (73.3%) were<br>females and 4 (26.7%) were males (male to female<br>ratio was 1:2.75). Only 2 out of 15 cases (13.3%) with<br>parasitic infestation had inflammation, whereas in<br>456 of the remaining non-parasitic appendices, 324<br>(71.1%) were positive for inflammation. This<br>difference was statistically significant with a p value<br>< 0.05.<br>Conclusion: Frequency of parasitic infestations in<br>surgically removed appendices is low. Very few<br>appendices with parasitic infestation are associated<br>with inflammation as compared to appendices<br>without parasites.</p>}, number={1}, journal={Journal of Rawalpindi Medical College}, author={Muhammad Arham, Muhammad Arish, Jahangir Sarwar Khan}, year={2018}, month={Mar.} }