Official publication of Rawalpindi Medical University
Impact of Topical Nepafenac on Macular Thickness after Phacoemulsification with Intraocular Lens Implantation in Patients without Diabetic Retinopathy
PDF

How to Cite

1.
Arooj Amjad, Muhammad Shaheer, Hassan Tariq, Ammarah Rasheed AAMSHTAR. Impact of Topical Nepafenac on Macular Thickness after Phacoemulsification with Intraocular Lens Implantation in Patients without Diabetic Retinopathy. JRMC [Internet]. 2023 Jan. 6 [cited 2024 Mar. 29];26(2). Available from: http://www.journalrmc.com/index.php/JRMC/article/view/1877

Abstract

Objective: To study the effect of post-operative Non-Steroidal Anti-inflammatory (NSAID) eye drops on macular
thickness in patients without diabetic retinopathy measured by Optical Coherence Tomography (OCT) after
cataract surgery.
Study Design: Quasi-experimental study.
Place & Duration of Study: Ophthalmology Department/Lahore General Hospital, Lahore from 15-01-2019 to
31-12-2021.
Materials & Methods: Diabetic patients without retinopathy who required cataract surgery for visual
rehabilitation were included in the study. They were then divided into two groups. Group A included patients
who received routine steroid+antibiotic post-operative drops while Group B comprised patients who received
nepafenac (0.1%) eye drops eight hourly in addition to routine post-operative eye drops. All patients underwent
standard phacoemulsification and intraocular lens implantation followed by the use of NSAID eye drops for a
month. OCT measurements were done pre-operatively, 7 and 28 days post-operatively.
Results: Comparison of central macular thickness between groups was significant at (Pre & 7-day post-op) and
insignificant at (7th day & 28th day post-op) and (Pre & 28th day post op) i.e. 0.043, 0.834, and 0.084 respectively.
However, a difference in mean central macular thickness was significant in all follow-up periods i.e. 0.003, 0.006,
and 0.000
Conclusion: Post-operative NSAID in diabetic patients without retinopathy leads to a significant decrease in
macular thickness as compared to those who do not receive post-operative NSAID after cataract surgery.
Keywords: Phacoemulsification, Optical Coherence Tomography, Non-steroidal Anti-Inflammatory Agents.

https://doi.org/10.37939/jrmc.v26i2.1877
PDF
Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Copyright (c) 2022 Arooj Amjad, Muhammad Shaheer, Hassan Tariq, Ammarah Rasheed