A Mosaic of Risk Factors for Female Infertility in Pakistan

  • Dua Zhaira College of Medical Lab Technology, Rawalpindi Medical University
  • Asma Nafisa Department of Pathology Benazir Bhutto Hospital and Rawalpindi Medical University , Rawalpindi
  • Nadeem Ikram Department of Pathology Benazir Bhutto Hospital and Rawalpindi Medical University , Rawalpindi
Keywords: Infertility, Hypertension, Hyperprolactenemia, Luteinizing hormone, Follicle- stimulating hormone

Abstract

Background: To identify different risk factors for
female infertility including hormonal imbalance
(FSH, LH and Prolactin)
Methods: Infertile women were enrolled in this
prospective study. A questionnaire was designed to
collect information regarding socio-demographic and
clinical characteristics of the study participants.
Serum FSH, LH and Prolactin levels were estimated
between 1-5 days of post menstrual period.
Independent sample t- test, Spearman correlation
and multivariate logistic regression were performed
to find the association of different risk factors with
female infertility.
Results: Highest percentage (57.7%) of infertile
females was in the age bracket of 26 to 35 years. The
prevalence of primary infertility was 60.4% . Mean
levels of LH and prolactin were significantly higher
in women with primary infertility compared to those
with secondary infertility. No significant difference
was observed in the mean level of FSH . A
significant positive correlation was found between
infertility and age , marital history and infertility
duration. On multivariate logistic regression
analysis women with secondary infertility were
more likely to be
hypertensive(OR=2.126,95%CI:1.020-4.474, p-
value0.044), using contraceptive OR = 5.876, 95% CI:
2.491–13.86, p-value .001),have hyperprolactenemia
(OR=1.289,95%CI:0.960-1.996,p-value0.001) and have
marital history of more than 16 years
OR=12.166,95%CI:5.048-29.322, p-value0.001).
Conclusion:Highest prevalence of infertility was
seen in the age group of 26-35 years. Advanced age,
hypertension, hyperprolactemia, use of contraceptive
and marital history of more than 16 years are
significantly associated with female infertility

Published
2019-05-02
How to Cite
Zhaira, D., Nafisa, A., & Ikram, N. (2019). A Mosaic of Risk Factors for Female Infertility in Pakistan. Journal of Rawalpindi Medical College, 23(2), 80-84. Retrieved from http://www.journalrmc.com/index.php/JRMC/article/view/1102
Section
Articles